骨膜蛋白(POSTN)單克隆抗體
Monoclonal Antibody to Periostin (POSTN)
OSF-2; PDLPOSTN; PN; Osteoblast Specific Factor 2
- 編號(hào)MAH339Hu21
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(jià)(克隆號(hào))C6
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標(biāo)記物無標(biāo)記物
- 免疫原RPH339Hu01-骨膜蛋白(POSTN)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/ml
- 且適物種Rattus norvegicus (Rat，大鼠)
- 應(yīng)用WB; ICC/IF
如果抗體需用于流式細(xì)胞術(shù)，請(qǐng)參見流式抗體。 - 下載英文說明書 中文說明書
- 規(guī)格20μl100μl200μl1ml10ml
- 價(jià)格¥ 666¥ 1554¥ 2220¥ 5550¥ 22200
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
IHC圖
AF488 staining on IF;<br/>Sample: Hela cell<br/>Primary Ab: 30μg/mL Mouse Anti-Human POSTN Antibody<br/>Second Ab: 2μg/mL AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody<br/>(Catalog: SAA544Mu11)
Figure. Western Blot; Sample: Recombinant POSTN, Human.
Western Blot; Sample: Lane1: Human Placenta lysate; Lane2: Human Lung lysate; Lane3: Rat Lung lysate<br/>Primary Ab: 3μg/mL Mouse Anti-Human POSTN Antibody<br/>Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody<br/>(Catalog: SAA544Mu19)
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
特異性
該抗體是針對(duì)POSTN的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別POSTN。
用法
Western blotting: 0.01-3μg/mL;
Immunocytochemistry: 5-30μg/mL;
Optimal working dilutions must be determined by end user.
儲(chǔ)存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
贈(zèng)品
增值服務(wù)
抗體標(biāo)記定制服務(wù)
Protein-A/G純化柱
細(xì)胞和組織染色液
抗體陽性對(duì)照品
組織/切片定制服務(wù)
磷酸化抗體定制服務(wù)
免疫印跡(WB)實(shí)驗(yàn)服務(wù)
免疫組織化學(xué)(IHC)實(shí)驗(yàn)服務(wù)
免疫細(xì)胞化學(xué)(ICC)實(shí)驗(yàn)服務(wù)
流式細(xì)胞術(shù)(FCM)實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
免疫熒光(IF)實(shí)驗(yàn)服務(wù)
緩沖液
DAB顯色試劑盒
SABC試劑盒
長臂生物素標(biāo)記試劑盒
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPH339Hu03 | 骨膜蛋白(POSTN)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPH339Hu01 | 骨膜蛋白(POSTN)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPH339Hu02 | 骨膜蛋白(POSTN)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAH339Hu01 | 骨膜蛋白(POSTN)多克隆抗體 | WB; IHC |
| PAH339Hu02 | 骨膜蛋白(POSTN)多克隆抗體 | WB; IHC; ICC; IP. |
| PAH339Hu03 | 骨膜蛋白(POSTN)多克隆抗體 | IHC |
| FAH339Hu01 | 抗骨膜蛋白(POSTN)多克隆抗體 | FCM |
| LAH339Hu71 | 骨膜蛋白(POSTN)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| MAH339Hu23 | 骨膜蛋白(POSTN)單克隆抗體 | IHC; ICC/IF |
| MAH339Hu24 | 骨膜蛋白(POSTN)單克隆抗體 | WB |
| MAH339Hu21 | 骨膜蛋白(POSTN)單克隆抗體 | WB; ICC/IF |
| MAH339Hu27 | 骨膜蛋白(POSTN)單克隆抗體 | WB |
| MAH339Hu29 | 骨膜蛋白(POSTN)單克隆抗體 | ICC/IF |
| MAH339Hu22 | 骨膜蛋白(POSTN)單克隆抗體 | WB; ICC/IF |
| SEH339Hu | 骨膜蛋白(POSTN)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMH339Hu | 骨膜蛋白(POSTN)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Blood | Circulating Periostin Is Elevated In Patients With Hemoglobinopathies and Correlates With Bone Mineral Density In Double Heterozygous Sickle-Cell/Beta-Thalassemia Patients; A Novel Marker Of Bone Strength?[Bloodjournal: Source] |
| The Journal of Clinical Endocrinology & Metabolism | Serum periostin is associated with fracture risk in postmenopausal women: a 7 years prospective analysis of the OFELY study[Pubmed: 24628551] |
| J Clin Endocrinol Metab. | Serum Periostin Is Associated With Fracture Risk in Postmenopausal Women: A 7-Year Prospective Analysis of the OFELY Study[Pubmed:24628551] |
| Rheumatology (Oxford). | Circulating periostin levels in patients with AS: association with clinical and radiographic variables, inflammatory markers and molecules involved in bone formation[Pubmed:25349442] |
| Journal of Periodontal Research | Assessment of periostin levels in serum and gingival crevicular fluid of patients with periodontal disease[Pubmed:25529858] |
| 新醫(yī)學(xué) | 血清內(nèi)脂素水平與多囊卵巢綜合征的相關(guān)性研究[Xinyixue:Source] |
| Osteoarthritis | Serum periostin is associated with prevalent knee osteoarthritis and disease incidence/progression in women: the OFELY study[PubMed: 26072384] |
| Endocrine | Serum periostin is a potential biomarker for non-alcoholic fatty liver disease: a case– control study[PubMed: 26362060] |
| Blood?Cancer?Journal | High levels of periostin correlate with increased fracture rate, diffuse MRI pattern, abnormal bone remodeling and advanced disease stage in patients with newly …[pubmed:27716740] |
| Metabolism.? | Low periostin levels in adult patients with Langerhans cell histiocytosis are independently associated with the disease activity.[pubmed:28521873] |
| Osteoporosis International | Circulating periostin levels increase in association with bone density loss and healing progression during the early phase of hip fracture in Chinese older women[pubmed:28382553] |
| Molecular Diagnosis & Therapy | The Utility of Biomarkers in Osteoporosis Management[pubmed:28271451] |
| Journal of Bone and Mineral Research | Cortical and trabecular bone microstructure did not recover at weight-bearing skeletal sites and progressively deteriorated at non-weight-bearing sites during the year following International Space Station missions[doi:10.1002] |
| Clinical Cases in Mineral and Bone Metabolism | Periostin and sclerostin levels in juvenile Paget's disease[pubmed:29263750] |
| Calcified?Tissue?International | Development of a New Immunoassay for Human Cathepsin K-Generated Periostin Fragments as a Serum Biomarker for Cortical Bone[pubmed:28725907] |
| Wiley | Characterization of a sandwich ELISA for the quantification of all human periostin isoforms[pubmed:28493527] |
| International Osteoporosis Foundation and National Osteoporosis Foundation | Interaction between LRP5 and periostin gene polymorphisms on serum periostin levels and cortical bone microstructure[pubmed:29038835] |
| Bone | Effect of age and gender on serum periostin: Relationship to cortical measures, bone turnover and hormones[pubmed:28323143] |
| Clinica Chimica Acta | Association between serum periostin concentrations and outcome after acute spontaneous intracerebral hemorrhage[pubmed:28882488] |
| Clinica Chimica Acta | Serum periostin concentrations and outcomes after severe traumatic brain injury[pubmed:28668564] |
| Tumor Biology | Predictive and prognostic value of serum periostin in advanced non–small cell lung cancer patients receiving chemotherapy[pubmed:28459197] |
| Journal of Bone and Mineral Research | Serum Levels of a Cathepsin-K Generated Periostin Fragment Predict Incident Low-Trauma Fractures in Postmenopausal Women Independently of BMD and FRAX[pubmed:28766739] |
| ОСОБЕННОСТИ СОСТОЯНИЯ ЗДОРОВЬЯ НОВОРОЖДЕННЫХ, РОЖДЕННЫХ ОТ МАТЕРЕЙ С БРОНХИАЛЬНОЙ АСТМОЙ[2017; 62:(4)] | |
| Endocrine | Circulating periostin in patients with nonalcoholic fatty liver disease.[pubmed:27738886] |
| Molecular Medicine Reports | Periostin cross?reacts with the renin?angiotensin system during liver fibrosis development[pubmed:28849131] |
| The Journal of Biological Chemistry | Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice[Pubmed:29929978] |
| Calcified?Tissue?International | The C-Terminal Intact Forms of Periostin (iPTN) Are Surrogate Markers for Osteolytic Lesions in Experimental Breast Cancer Bone Metastasis[Pubmed:29916127] |
| Journal of Endocrinological Investigation | Increased serum periostin concentrations are associated with the presence of diabetic retinopathy in patients with type 2 diabetes mellitus[Pubmed:29349642] |
| Wiener klinische Wochenschrift | Rheumatoid arthritis in remission[] |
| Clinical?and Experimental Medicine | Myostatin and other musculoskeletal markers in lung transplant recipients[Pubmed: 30317402] |
| Experimental?and?Clinical?Endocrinology?&?Diabetes | Polycystic Ovary Syndrome is Associated with Elevated Periostin Levels[Pubmed: 30372763] |
| ИСПОЛЬЗОВАНИЕ СЫВОРОТОЧНОГО ПЕРИОСТИНА В КАЧЕСТВЕ МАРКЕРА ОБОСТРЕНИЙ АСТМЫ У ДЕТЕЙ[] | |
| Bone | Tartrate-resistant acid phosphatase 5b, but not periostin, is useful for assessing Paget's disease of bone[Pubmed: 31051316] |
| Journal of Clinical Laboratory Analysis | Identification and diagnostic value of pleural fluid periostin and serum periostin of malignant pleural effusions in patients with non–small‐cell lung cancer[Pubmed: 31268191] |
| Bone | Serum periostin is associated with cancer mortality but not cancer risk in older home-dwelling men: A 8-year prospective analysis of the STRAMBO study[Pubmed: 31812700] |
| FASEB J | Fibronectin rescues aberrant phenotype of endothelial cells lacking either CCM1, CCM2 or CCM3[Pubmed: 32515053] |
| Journal of Reproductive Immunology | Serum and placental periostin levels in women with early pregnancy loss[Pubmed: 32460058] |
| Annals of Medical Research | Evaluation of periostin levels in gingival crevicular fluid and peri-implant sulcus fluid in patients with periodontal and peri-implanter disease: A cross-sectional?…[] |
| Myostatin and Markers of Bone Metabolism in Dermatomyositis[] | |
| Am J Physiol Heart Circ Physiol | Periostin promotes arterial calcification through PPAR|?-related glucose metabolism reprogramming[33834866] |
| International Journal of Chronic Obstructive Pulmonary Disease | High Blood Eosinophil and YKL-40 Levels, as Well as Low CXCL9 Levels, are Associated with Increased Readmission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease[33814903] |
| J Bone Oncol | Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma[34150488] |
| Rambam Maimonides Med J | The Relationship between Serum Periostin Levels and Neutrophil¨CLymphocyte Ratio with Lesion Localization and Acute Prognosis in Acute Ischemic Stroke[34137680] |
| Rambam Maimonides Medical Journal | First Admission Neutrophil–Lymphocyte Ratio May Indicate Acute Prognosis of Ischemic Stroke[34137680] |