胱天蛋白酶3(CASP3)檢測試劑盒(酶聯(lián)免疫吸附試驗法)
ELISA Kit for Caspase 3 (CASP3)
CPP32; CPP32B; SCA1; Apoptain; Yama; Apoptosis-Related Cysteine Peptidase; Cysteinyl Aspartate Specific Proteinases 3; SREBP cleavage activity 1
- 編號SEA626Hu
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 實驗方法雙抗夾心
- 反應(yīng)時長3h
- 檢測范圍0.156-10ng/mL
- 靈敏度最小可檢測劑量小于等于0.061ng/mL.
- 樣本類型tissue homogenates, cell lysates, cell culture supernates and other biological fluids
- 下載英文說明書 中文說明書
- 規(guī)格48T96T96T*596T*1096T*100
- 價格¥ 2646¥ 3780¥ 17010¥ 32130¥ 264600
- 欲了解實際交易價格和更多情況，請與當(dāng)?shù)亟?jīng)銷商聯(lián)系!
產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
實驗結(jié)果圖
標準曲線圖
通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
本試劑盒用于檢測胱天蛋白酶3(CASP3)，經(jīng)檢測與其它相似物質(zhì)無明顯交叉反應(yīng)。
由于受到技術(shù)及樣本來源的限制，不可能完成對所有相關(guān)或相似物質(zhì)交叉反應(yīng)檢測，因此本試劑盒有可能與未經(jīng)檢測的其它物質(zhì)有交叉反應(yīng)。
精密度
精密度用樣品測定值的變異系數(shù)CV表示。CV(%) = SD/mean×100
批內(nèi)差：取同批次試劑盒對低、中、高值定值樣本進行定量檢測,每份樣本連續(xù)測定20 次，分別計算不同濃度樣本的平均值及SD值。
批間差：選取3個不同批次的試劑盒分別對低、中、高值定值樣本進行定量測定，每個樣本使用同一試劑盒重復(fù)測定8次，分別計算不同濃度樣本的平均值及SD值。
批內(nèi)差： CV<10%
批間差： CV<12%
穩(wěn)定性
經(jīng)測定，試劑盒在有效期內(nèi)按推薦溫度保存，其活性降低率小于5%。
為減小外部因素對試劑盒破壞前后檢測值的影響，實驗室的環(huán)境條件需盡量保持一致，尤其是實驗室內(nèi)溫度、濕度及溫育條件。其次由同一實驗員來進行操作可減少人為誤差。
實驗流程
1. 實驗前標準品、試劑及樣本的準備；
2. 加樣（標準品及樣本）100µL，37°C孵育1小時；
3. 吸棄，加檢測溶液A100µL，37°C孵育1小時；
4. 洗板3次；
5. 加檢測溶液B100µL，37°C孵育30分鐘；
6. 洗板5次；
7. 加TMB底物90µL，37°C孵育10-20分鐘；
8. 加終止液50µL，立即450nm讀數(shù)。
實驗原理
將胱天蛋白酶3(CASP3)抗體包被于96孔微孔板中，制成固相載體，向微孔中分別加入標準品或標本，其中的胱天蛋白酶3(CASP3)與連接于固相載體上的抗體結(jié)合，然后加入生物素化的胱天蛋白酶3(CASP3)抗體，將未結(jié)合的生物素化抗體洗凈后，加入HRP標記的親和素，再次徹底洗滌后加入TMB底物顯色。TMB在過氧化物酶的催化下轉(zhuǎn)化成藍色，并在酸的作用下轉(zhuǎn)化成最終的黃色。顏色的深淺和樣品中的胱天蛋白酶3(CASP3)呈正相關(guān)。用酶標儀在450nm波長下測定吸光度(O.D.值)，計算樣品濃度。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| APA626Hu01 | 胱天蛋白酶3(CASP3)活性蛋白 | Cell?culture;?Activity?Assays. |
| RPA626Hu01 | 胱天蛋白酶3(CASP3)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA626Hu02 | 胱天蛋白酶3(CASP3)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA626Hu03 | 胱天蛋白酶3(CASP3)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA626Hu03 | 胱天蛋白酶3(CASP3)多克隆抗體 | WB |
| PAA626Hu02 | 胱天蛋白酶3(CASP3)多克隆抗體 | WB; IHC |
| PAA626Hu01 | 胱天蛋白酶3(CASP3)多克隆抗體 | WB; IHC |
| LAA626Hu81 | 胱天蛋白酶3(CASP3)多克隆抗體(異硫氰酸熒光素標記) | WB; IHC; ICC; IF. |
| LAA626Hu71 | 胱天蛋白酶3(CASP3)多克隆抗體(生物素標記) | WB; IHC; ICC. |
| MAA626Hu21 | 胱天蛋白酶3(CASP3)單克隆抗體 | WB; IHC |
| MAA626Hu22 | 胱天蛋白酶3(CASP3)單克隆抗體 | WB |
| SEA626Hu | 胱天蛋白酶3(CASP3)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA626Hu | 胱天蛋白酶3(CASP3)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| KSA626Hu01 | 胱天蛋白酶3(CASP3)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻
| 雜志 | 參考文獻 |
| International Journal of Biological Sciences | Protective Effects of Morus alba Leaves Extract on Ocular Functions of Pups from Diabetic and Hypercholesterolemic Mother Rats[PubMed: 21697998] |
| Reprod Sci. | Role of mitochondria in ciprofloxacin-induced apoptosis in murine sperm cells.[Pubmed: 23420823] |
| European journal of pharmacology | The combined effect of metformin and L-cysteine on inflammation, oxidative stress and insulin resistance in streptozotocin-induced type 2 diabetes in rats[Pubmed: 23845213] |
| Journal of Physiology and Biochemistry | Vitamin D ameliorates hepatic ischemic/reperfusion injury in rats[Springer: Source] |
| Life Sci. | Attenuation of renal ischemia/reperfusion injury by a?aí extract preconditioning in a rat model[Pubmed:25476829] |
| Toxicol Appl Pharmacol.? | Amelioration of nandrolone decanoate-induced testicular and sperm toxicity in rats by taurine: Effects on steroidogenesis, redox and inflammatory cascades, and intrinsic apoptotic pathway[Pubmed:25542992] |
| Journal of Traditional and Complementary Medicine | Antioxidant effects of Spirulina supplement against lead acetate-induced hepatic injury in rats[Sciencedirect:S2225411015000231] |
| J Physiol Biochem. | Vitamin D ameliorates hepatic ischemic/reperfusion injury in rats[Pubmed:24752458] |
| Molecular Biology Reports | Apoptotic effects of dipyrido [3,2-a:2',3'-c] phenazine (dppz) Au(III) complex against diethylnitrosamine/phenobarbital induced experimental hepatocarcinogenesis in rats[Pubmed:24756331] |
| Life Sciences | Pomegranate extract protects against cerebral ischemia/reperfusion injury and preserves brain DNA integrity in rats[Pubmed:25010842] |
| European Journal of Pharmacology | Neuroprotective effects of rosuvastatin against traumatic spinal cord injury in rats[Pubmed:25084223] |
| J Investig Clin Dent. | Expression of key executioner of apoptosis caspase?\3 in periodontal health and disease[Pubmed:25388853] |
| Neuropharmacology | Saxagliptin: A novel antiparkinsonian approach[Pubmed:25446674] |
| Molecular Neurobiology | Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson’s Disease: Modulation of Mitochondrial Perturbations[Pubmed:25502462] |
| Histochem Cell Biol. | Inhibition of small HA fragment activity and stimulation of A2A adenosine receptor pathway limit apoptosis and reduce cartilage damage in experimental arthritis[Pubmed:25511416] |
| Protective role of ellagitannins from Eucalyptus citriodora against ethanol-induced gastric ulcer in rats: Impact on oxidative stress, inflammation and calcitonin-gene related peptide[Pubmed:25636864] | |
| Biochemical Pharmacology | Epigallocatechin-3-gallate pretreatment attenuates doxorubicin-induced cardiotoxicity in rats: A mechanistic study[Pubmed:25701654] |
| Journal of Pharmacology Research | CILOSTAZOL HEPATOPROTECTIVE EFFECT AGAINST ISCHEMIA/REPERFUSION: INVOLVEMENT OF GSK-3β, CYCLIN D1 and WNT/β-CATENIN PATHWAY[Researchgate:Source] |
| Life Sciences | Attenuation of renal ischemia/reperfusion injury by a[PubMed: 25476829] |
| Injury | Neuroprotective[PubMed: 26298021] |
| PLOS ONE | Antidiabetic Effect of Galantamine: Novel Effect for a Known Centrally Acting Drug[PubMed: 26262991] |
| Histochem Cell Biol | Inhibition of small HA fragment activity and stimulation of A2A[PubMed: 25511416] |
| PLOS ONE | BDNF-TrkB Pathway Mediates Neuroprotection of Hydrogen Sulfide against Formaldehyde-Induced Toxicity to PC12 Cells[PubMed: 25749582] |
| Life Sci | Geraniol ameliorates TNBS-induced colitis: Involvement of Wnt/棺-catenin, p38MAPK, NF觀B, and PPAR款 signaling pathways[PubMed: 26165751] |
| Naunyn Schmiedebergs Arch Pharmacol | The multi-kinase inhibitor pazopanib targets hepatic stellate cell activation and apoptosis alleviating progression of liver fibrosis[PubMed: 26269412] |
| Pharmacological Reports | The heat shock protein 90 inhibitor, 17-AAG, attenuates thioacetamide induced liver fibrosis in mice[Science: Article] |
| European Journal of Medicinal Plants | Hepatoprotective Effects of Rubus idaeus L. Leaves against CCl4-Induced Liver Injury via Antioxidant, Anti-inflammatory and Antiapoptotic Mechanisms[openview:626440] |
| Chemico-Biological Interactions | Crocin protects against doxorubicin-induced myocardial toxicity in rats through down-reCavia (Guinea pig )lation of inflammatory and apoptic pathways[Pubmed:26807765] |
| Oncotarget | An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimers mouse model[Pubmed:27144524] |
| Journal of Food Science | Correlation of In Vivo and In Vitro Assay Results for Assessment of Free Radical Scavenging Activity of Green Tea Nutraceuticals[Pubmed:27275932] |
| Journal of Natural Medicines | Anti-oxidative, anti-secretory and anti-inflammatory activities of the extract from the root bark of Lycium chinense (Cortex Lycii) against gastric ulcer in mice[Pubmed:26972100] |
| Iranian Journal of Basic Medical Sciences | Neuroprotective effects of atomoxetine against traumatic spinal cord injury in rats[pmc:PMC4834117] |
| IJBPAS | THE PROPHYLACTIC EFFICIENCY OF LYCOPENE AGAINST GAMMA IRRADAITION-INDIUCED CARDIAC OXIDATIVE DAMAGE, PATHOLOGY AND APOPTOSIS IN RATS[publication:298838934] |
| Neurochem Res. | Arecoline Induces Neurotoxicity to PC12 Cells: Involvement in ER Stress and Disturbance of Endogenous H2S Generation[Pubmed:27255601] |
| Original Investigation | Neuroprotective Effects of Pregabalin Against Spinal Cord Ischemia-Reperfusion Injury in Rats[JTNEPUB:17959] |
| Molecules | Clematichinenoside (AR) Attenuates Hypoxia/Reoxygenation-Induced H9c2 Cardiomyocyte Apoptosis via a Mitochondria-Mediated Signaling Pathway[Pubmed:27248986] |
| Springerplus. | The hepatocurative effects of Cynara scolymus L. leaf extract on carbon tetrachloride-induced oxidative stress and hepatic injury in rats[Pubmed:27026910] |
| Oncotarget | Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE?/? alzheimer mouse model[pubmed:27708245] |
| Journal of traditional and complementary medicine. | Antioxidant effects of Spirulina supplement against lead acetate-induced hepatic injury in rats.[pubmed:27774414] |
| pharmaceutical biology | Protective effects of apigenin and myricetin against cisplatin-induced nephrotoxicity in mice.[pubmed:28064632] |
| Toxicology and Applied Pharmacology | Dapoxetine attenuates testosterone-induced prostatic hyperplasia in rats by the regulation of inflammatory and apoptotic proteins[pubmed:27687055] |
| Journal of Natural Medicines | Anti-oxidative,?anti-secretory?and?anti-inflammatory?activities?of the?extract?from the?root?bark?ofLycium?chinense?(Cortex Lycii) against gastric ulcer in mice.[pubmed:26972100] |
| BMC Cancer | Saikosaponin?d?induces?cell?death?through?caspase-3-dependent,?caspase-3-independent?andmitochondrial?pathways?in?mammalian?hepatic?stellate?cells.[pubmed:27461108] |
| Neurochemical?Research | Arecoline Induces Neurotoxicity to PC12 Cells: Involvement in ER Stress and Disturbance of Endogenous H2S Generation.[pubmed:27255601] |
| Molecular Medicine Reports | Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting the expression of peroxiredoxin III in H9c2 cells[mmr:13] |
| The American Journal of Chinese Medicine | Saikosaponin a Induces Apoptosis through Mitochondria-Dependent Pathway in Hepatic Stellate Cells[pubmed:28231747] |
| bmc musculoskeletal disorders | Strontium ranelate causes osteophytes overgrowth in a model of early phase osteoarthritis.[pubmed:28187731] |
| Journal?of?Ethnopharmacology | Amelioration?of?cardiac?dysfunction?and?ventricular?remodeling?after?myocardial?infarction?bydanhong?injection?are?critically?contributed by anti-TGF-β-mediated fibrosis and angiogenesis mechanisms.[pubmed:27729285] |
| Food and Chemical Toxicology | Chrysin attenuates testosterone-induced benign prostate hyperplasia in rats[pubmed:29247772] |
| Journal of Molecular Biomarkers J & Diagnosis | Role of Pomegranate Juice and Atorvastatin in Ameliorating Spinal Neurotoxicity of Wistar Rats Maternally Fed on Hypercholesterolemic Diet[DOI: 10.4172/2155-9929.1000316] |
| Cellular Physiology and Biochemistry | A Novel Role of SIRT1/ FGF-21 in Taurine Protection Against Cafeteria Diet-Induced Steatohepatitis in Rats[pubmed:28942443] |
| International Journal of Biological Macromolecules | A polysaccharide (PNPA) from Pleurotus nebrodensis ameliorates hepatic ischemic/reperfusion (I/R) injury in rats[pubmed:28709897] |
| Experimental and Therapeutic Medicine | Tectorigenin attenuates the MPP+ induced SH?SY5Y cell damage, indicating a potential beneficial role in Parkinson's disease by oxidative stress inhibition[pubmed:29067118] |
| Biomedical Research | Pitavastatin inhibits proinflammatory cytokines and provides improvement in terms of its motor function in secondary injuries of the spinal cord mouse models[ISSN 0970-938X] |
| Chemico-Biological Interactions | Modulatory effect of silymarin on nuclear factor-erythroid-2-related factor 2 regulated redox status, nuclear factor-κB mediated inflammation and apoptosis in experimental gastric ulcer[10.1016/j.cbi.2017.06.022] |
| Frontiers in Pharmacology | Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus.[pubmed:28553224] |
| Journal of Inorganic Biochemistry | Biomimetic fabrication of antibacterial calcium phosphates mediated by polydopamine. [pubmed:29049953] |
| Indian Journal of Pharmaceutical Sciences | Hepatoprotective Activities of the Methanol Extract of Angelica shikokiana and Isoepoxypteryxin against Hepatocellular Carcinoma[DOI: 10.4172/pharmaceutical-sciences.1000265] |
| Theranostics | Drug-delivering-drug platform-mediated potent protein therapeutics via a non-endo-lysosomal route[Pubmed:30026860] |
| Food and Chemical Toxicology | Antioxidant, anti-inflammatory and synergistic anti-hyperglycemic effects of Malaysian propolis and metformin in streptozotocin–induced diabetic rats[Pubmed:30026088] |
| Life Sciences | Nephroprotective effect of saxagliptin against gentamicin-induced nephrotoxicity, emphasis on anti-oxidant, anti-inflammatory and anti-apoptic effects[Pubmed:30012474] |
| Journal of Ethnopharmacology | Viscum articulatum Burm. f. aqueous extract exerts antiproliferative effect and induces cell cycle arrest and apoptosis in leukemia cells[Pubmed:29555410] |
| Journal?of?Medicinal?Food | Posttreatment Effects of L. Leaf Extract on Carbon Tetrachloride-Induced Liver Injury and Oxidative Stress in Rats[Pubmed:29648970] |
| Reproductive?Biology | Anti-hypercholesterolemic impacts of barley and date palm fruits on the ovary of Wistar albino rats and their offspring[Pubmed:30005909] |
| BMC?Pharmacology and Toxicology | Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis[Pubmed:29321061] |
| Toxics | Zinc Oxide Nanoparticles Induced Oxidative DNA Damage, Inflammation and Apoptosis in Rat's Brain after Oral Exposure[Pubmed:29861430] |
| Avicenna?Journal of?Medical?Biotechnology | Apoptosis of Adipose-Derived Stem Cells Induced by Liposomal Soybean Phosphatidylcholine Extract[Pubmed:30090204] |
| Biological?Trace?Element?Research | Effect of Aqueous Extract of?Glycyrrhiza glabra?on the Biochemical Changes Induced by Cadmium Chloride in Rats[Pubmed: 30251228] |
| Environmental?Toxicology | Potential immunomodulatory and antioxidant effects of walnut ?vegetable oil against lead‐mediated hepatic damage and their interaction with lipase?…[Pubmed: 30251767] |
| Life?Sciences | Malaysian propolis, metformin and their combination, exert hepatoprotective effect in streptozotocin-induced diabetic rats[Pubmed: 30205096] |
| AAPS?PharmSciTech | Augmentation of Fluvastatin Cytotoxicity Against Prostate Carcinoma PC3 Cell Line Utilizing Alpha Lipoic–Ellagic Acid Nanostructured Lipid Carrier Formula[Pubmed: 30350252] |
| Naunyn-Schmiedeberg's Archives of Pharmacology | Side effects of frequently used oral antidiabetics on wound healing in vitro[Pubmed: 30535571] |
| Archives of Physiology and Biochemistry | Diabetes-induced testicular oxidative stress, inflammation, and caspase-dependent apoptosis: the protective role of metformin[Pubmed: 30513216] |
| Acta?Biochimica et?Biophysica Sinica | Adiponectin attenuates lipopolysaccharide-induced cell injury of H9c2 cells by regulating AMPK pathway[Pubmed: 30668810] |
| Food and Chemical Toxicology | Gum Acacia mitigates diclofenac nephrotoxicity by targeting monocyte chemoattractant protein-1, complement receptor-1 and pro-apoptotic pathways[Pubmed: 31042592] |
| Environmental Toxicology | Antihepatocarcinogenic activity of whey protein concentrate and lactoferrin in diethylnitrosamine‐treated male albino mice[Pubmed: 31087429] |
| Biological trace element research | High Concentrations of Boric Acid Trigger Concentration-Dependent Oxidative Stress, Apoptotic Pathways and Morphological Alterations in DU-145 Human Prostate?…[Pubmed: 31066018] |
| Skin pharmacology and physiology | Side Effects of Frequently Used Antihypertensive Drugs on Wound Healing in vitro[Pubmed: 31018213] |
| Iranian?Journal?of?Pharmaceutical?Research | Therapeutic effects of nano-HAp in a rat model of AlCl3 induced neurotoxicity[Doi: 10.22037/IJPR.2019.1100760] |
| International Journal of Pharmaceutical Research & Allied Sciences | Prophylactic Impact of Beta vulgaris L in Ameliorating Cyclosporine A-Induced Hepatotoxicity in Rats.[] |
| Effect of gamma radiation on combination therapy of certain antiepileptic drugs in rats.[] | |
| Journal of Food Biochemistry | Dietary supplementation of barley and/or dates attenuate hypercholesterolemic‐induced endometrial dysfunction in Wistar albino rats via alleviation of apoptotic?…[Pubmed: 31373029] |
| Antioxidants (Basel). | The Effect of Dietary Quercetin on the Glutathione Redox System and Small Intestinal Functionality of Weaned Piglets[Pubmed: 31426309] |
| Biological Trace Element Research | The Role of Oxidative Stress, Renal Inflammation, and Apoptosis in Post Ischemic Reperfusion Injury of Kidney Tissue: the Protective Effect of Dose-Dependent Boric?…[] |
| Cell?Stress Chaperones | Betaine suppresses cell proliferation by increasing oxidative stress–mediated apoptosis and inflammation in DU-145 human prostate cancer cell line[Pubmed: 31368044] |
| Int Immunopharmacol | Metallothionein-1 is associated with osteoarthritis disease activity and suppresses proinflammatory cytokines production in synovial cells[Pubmed: 31465913] |
| Biological trace element research | Concentration-Dependent Effects of Zinc Sulfate on DU-145 Human Prostate Cancer Cell Line: Oxidative, Apoptotic, Inflammatory, and Morphological Analyzes[Pubmed: 31463762] |
| Naunyn-Schmiedeberg's Archives of Pharmacology | Carnosine and l-arginine attenuate the downregulation of brain monoamines and gamma aminobutyric acid; reverse apoptosis and upregulate the expression of?…[Pubmed: 31641819] |
| Antioxidants | Oxidative Stress, NF-κB-Mediated Inflammation and Apoptosis in the Testes of Streptozotocin–Induced Diabetic Rats: Combined Protective Effects of Malaysian?…[Pubmed: 31600920] |
| International Journal of Molecular Sciences | Encapsulation of Lovastatin in Zein Nanoparticles Exhibits Enhanced Apoptotic Activity in HepG2 Cells[Pubmed: 31752085] |
| Scientific Reports | Mebendazole augments sensitivity to sorafenib by targeting MAPK and BCL-2 signalling in n-nitrosodiethylamine-induced murine hepatocellular carcinoma[Pubmed: 31836811] |
| Pharmaceutics | Preparation and Optimization of In Situ Gel Loaded with Rosuvastatin-Ellagic Acid Nanotransfersomes to Enhance the Anti-Proliferative Activity[Pubmed: 32183144] |
| Photodiagnosis and Photodynamic Therapy | In vitro evaluation of cytotoxic properties of 5-Aminolevulinic acid (5-ALA) on bladder cancer cells[Pubmed: 32165337] |
| Frontiers in Neuroscience | Hydrogen Sulfide Prevents Sleep Deprivation-Induced Hippocampal Damage by Upregulation of Sirt1 in the Hippocampus[Pubmed: 32218719] |
| FASEB J | Bovine colostrum induces the differentiation of human primary keratinocytes[Pubmed: 32157742] |
| Marine Drugs | In Situ Gel Loaded with Chitosan-Coated Simvastatin Nanoparticles: Promising Delivery for Effective Anti-Proliferative Activity against Tongue Carcinoma[Pubmed: 32283782] |
| NAUNYN-SCHMIEDEBERGS?ARCHIVES OF?PHARMACOLOGY | Effects of repeated increasing doses of cisplatin as models of acute kidney injury and chronic kidney disease in rats[Pubmed: 32936352] |
| Pharmaceutics | Chitosan-Based Microparticles Enhance Ellagic Acid's Colon Targeting and Proapoptotic Activity[Pubmed: 32660035] |
| Life Sciences | Curcumin and LOXblock-1 ameliorate ischemia-reperfusion induced inflammation and acute kidney injury by suppressing the semaphorin-plexin pathway.[Pubmed: 32603817] |
| TOXICOLOGY | Tert-butylhydroquinone preserve testicular steroidogenesis and spermatogenesis in cisplatin-intoxicated rats by targeting oxidative stress, inflammation and apoptosis[Pubmed: 32565124] |
| International Journal of Molecular Sciences | Optimized Conjugation of Fluvastatin to HIV-1 TAT Displays Enhanced Pro-Apoptotic Activity in HepG2 Cells[Pubmed: 32531976] |
| analytical chemistry | Fast Activation and Tracing of Caspase-3 Involved Cell Apoptosis by Combined Electrostimulation and Smart Signal-Amplified SERS Nanoprobes[Pubmed: 32395992] |
| Mar Drugs | Chitosan Coated Microparticles Enhance Simvastatin Colon Targeting and Pro-Apoptotic Activity[Pubmed: 32344610] |
| BIOMEDICINE & PHARMACOTHERAPY | Protective effects of bee bread on testicular oxidative stress, NF-κB-mediated inflammation, apoptosis and lactate transport decline in obese male rats[Pubmed: 33152939] |
| Iranian Journal of Basic Medical Sciences | Chromon-3-aldehyde derivatives restore mitochondrial function in rat cerebral ischemia[Pubmed: 32963739] |
| International Journal of Research in Pharmaceutical | In situ gel loaded with curcumin-based fluvastatin nanostructured carrier effective against squamous tongue carcinoma[] |
| SAGE Journals | Insights Into Protective Mechanisms of Dandelion Leaf Extract Against Cisplatin-Induced Nephrotoxicity in Rats: Role of Inhibitory Effect on Inflammatory and Apoptotic?…[] |
| Bangladesh Journal of Pharmacology | Ethylmethylhydroxypyridine succinate, acetylcysteine and choline alphoscerate improve mitochondrial function under condition of cerebral ischemia in rat[] |
| International Journal of Pharmacology | Ellagic Acid Loaded TPGS Micelles for Enhanced Anticancer Activities in Ovarian Cancer[] |
| Strawberry (Fragaria x ananassa) leaf extract reduces brain damage in diabetic male rats[] | |
| Indian Journal of Animal Research | Accacia senegel extract ameliorates Lead Acetate-mediated Hepatotoxicity in rats.[] |
| RESEARCH SQUARE | Experimental Observation of the Sequence of Tibial Plateau Chondrocyte and Matrix Degeneration in Spontaneous Osteoarthritis in Guinea Pigs[] |
| Egyptian Journal of Basic and Applied Sciences | Fish-oil supplementation improves retinal injury induced by diabetes and hypercholesterolemia in male Wistar rats[] |
| ACTIVITY OF APOPTOSIS MARKERS IN HPV-ASSOCIATED CERVICAL PATHOLOGIES[] | |
| Norwegian Journal of development of the International Science | CLINICAL AND PATHOGENETIC SIGNIFICANCE OF CHANGES IN PURINE METABOLISM DURING LUNG CANCER [] |
| J Biochem Mol Toxicol | Concanavalin A induces apoptosis in a dose?\dependent manner by modulating thiol/disulfide homeostasis in C6 glioblastoma cells[33604990] |
| International Journal of Reproductive Medicine | Gonadotropin Stimulation Has Only a Limited Effect on the Concentration of Follicular Fluid Signalling Proteins: An Antibody Array Analysis[33575317] |
| Sci Rep | Tert-butylhydroquinone attenuates doxorubicin-induced dysregulation of testicular cytoprotective and steroidogenic genes, and improves spermatogenesis in rats[33750916] |
| TOXICOLOGY IN VITRO | Cyproheptadine causes apoptosis and decreases inflammation by disrupting thiol/disulfide balance and enhancing the levels of SIRT1 in C6 glioblastoma cells[33675893] |
| Biomed Pharmacother | Captopril downregulates expression of Bax/cytochrome C/caspase-3 apoptotic pathway, reduces inflammation, and oxidative stress in cisplatin-induced acute??-[33945910] |
| Reprod Sci | Reproductive Effects of Nicotinamide on Testicular Function and Structure in Old Male Rats: Oxidative, Apoptotic, Hormonal, and Morphological Analyses[34101148] |
| BMC Complement Med Ther | Effect of the standard herbal preparation, STW5, treatment on dysbiosis induced by dextran sodium sulfate in experimental colitis[34103031] |
| Environ Sci Pollut Res Int | Comparative effects of metformin and Cistus laurifolius L. extract in streptozotocin-induced diabetic rat model: oxidative, inflammatory, apoptotic, and histopathological??-[34097215] |
| Piceatannol Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by Modulation of Nrf2/HO-1/NF|êB Axis. Front. Pharmacol. 11: 614897. doi??-[33519479] | |
| Biomed Pharmacother | Allicin ameliorates renal ischemia/reperfusion injury via inhibition of oxidative stress and inflammation in rats[34426252] |
| Chem Biol Interact | Protective role of naringin loaded solid nanoparticles against aflatoxin B1 induced hepatocellular carcinoma[34717916] |
| Biochim Biophys Acta Gen Subj | Paraoxonase 2 protects against the CML mediated mitochondrial dysfunction through modulating JNK pathway in human retinal cells[34710487] |
| AAPS PharmSciTech | Development of an Icariin-Loaded Bilosome-Melittin Formulation with Improved Anticancer Activity against Cancerous Pancreatic Cells[34668089] |
| Analytical Cellular Pathology | The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia[34336554] |
| Ecotoxicol Environ Saf | Evaluation of cytogenotoxic potential and embryotoxicity of KRS-Cauvery River water in zebrafish (Danio rerio)[Pubmed:35183813] |
| Environ Sci Pollut Res Int | Chrysin attenuates estradiol-induced endometrial hyperplasia in rats via enhancing PPARα activity[Pubmed:35301625] |
| PLoS One | Neuroprotective effect of sodium alginate against chromium-induced brain damage in rats[Pubmed:35421180] |
| Journal of Ethnopharmacology | Ethnopharmacological impact of Melaleuca rugulosa (Link) Craven leaves extract on liver inflammation[Pubmed:35337921] |
| Eur J Pharmacol | Harmine prevents 3-nitropropionic acid-induced neurotoxicity in rats via enhancing NRF2-mediated signaling: Involvement of p21 and AMPK[Pubmed:35623405] |
| Gels | QbD Supported Optimization of the Alginate-Chitosan Nanoparticles of Simvastatin in Enhancing the Anti-Proliferative Activity against Tongue Carcinoma[Pubmed:35200484] |
| Naunyn-Schmiedeberg's Archives | Inflammatory Modulation of miR-155 Inhibits Doxorubicin?Induced Testicular Dysfunction Via Sirt1/Foxo1 Pathway: Insight to the Role of Acacetin and Bacillus?…[Pubmed:35715546] |
| Antioxidants | Therapeutic Effects of Bee Bread on Obesity-Induced Testicular-Derived Oxidative Stress, Inflammation, and Apoptosis in High-Fat Diet Obese Rat Model?…[Pubmed:35204140] |
| Value Health Sci | Oksidatif, Apoptotik ve ?nflamatuar Sinyal Yolaklar? üzerinden C6 Glioblastoma Hücrelerindeki ML351'in Antiproliferatif Etkileri[] |
| Impact de l'incorporation d'acides gras à chaine moyenne, de suppléments de levures et d'avoine nue sur la santé intestinale ainsi que sur la consommation?…[] | |
| Biointerface Research in Applied Chemistry | Promising Therapeutic Efficacy of Trigonella-foenum graecum and Bone Marrow-Derived Mesenchymal Stem Cells on Skeletal Muscle Atrophy in Experimental?…[] |
| Arab Journal of Nuclear Sciences and Applications | Potential activity of silver/hydroxyapatite nano composite against damaged liver consequence to irradiation[] |
